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On the Environmental Factors Affecting the Structural and Cytotoxic Properties of IAPP Peptides

Pancreatic islets in type 2 diabetes mellitus (T2DM) patients are characterized by reduced β-cells mass and diffuse extracellular amyloidosis. Amyloid deposition involves the islet amyloid polypeptide (IAPP), a neuropancreatic hormone cosecreted with insulin by β-cells. IAPP is physiologically invol...

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Detalles Bibliográficos
Autores principales:	Tomasello, Marianna Flora, Sinopoli, Alessandro, Pappalardo, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637107/ https://www.ncbi.nlm.nih.gov/pubmed/26582441 http://dx.doi.org/10.1155/2015/918573

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