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Nebulised dornase alfa versus placebo or hypertonic saline in adult critically ill patients: a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis

BACKGROUND: Nebulised dornase alfa is used off-label in critically ill patients. We aimed to assess the benefits and harms of nebulised dornase alfa versus placebo, no prophylaxis, or hypertonic saline on patient-important outcome measures in adult critically ill patients. METHODS: We performed a sy...

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Detalles Bibliográficos
Autores principales:	Claudius, Casper, Perner, Anders, Møller, Morten Hylander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637143/ https://www.ncbi.nlm.nih.gov/pubmed/26547839 http://dx.doi.org/10.1186/s13643-015-0142-z

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