The anticancer immune response of anti-PD-1/PD-L1 and the genetic determinants of response to anti-PD-1/PD-L1 antibodies in cancer patients

The programmed death-1 (PD-1), a coinhibitory receptor expressed on activated T cells and B cells, is demonstrated to induce an immune-mediated response and play a critical role in tumor initiation and development. The cancer patients harboring PD-1 or PD ligand 1 (PD-L1) protein expression have oft...

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Detalles Bibliográficos
Autores principales: Sui, Xinbing, Ma, Junhong, Han, Weidong, Wang, Xian, Fang, Yong, Li, Da, Pan, Hongming, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637293/
https://www.ncbi.nlm.nih.gov/pubmed/26305724

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