miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eμ-TCL1 mouse model

The involvement of microRNAs (miRNAs) in chronic lymphocytic leukemia (CLL) pathogenesis suggests the possibility of anti-CLL therapeutic approaches based on miRNAs. Here, we used the Eμ-TCL1 transgenic mouse model, which reproduces leukemia with a similar course and distinct immunophenotype as huma...

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Detalles Bibliográficos
Autores principales: Bresin, Antonella, Callegari, Elisa, D'Abundo, Lucilla, Cattani, Caterina, Bassi, Cristian, Zagatti, Barbara, Narducci, M. Grazia, Caprini, Elisabetta, Pekarsky, Yuri, Croce, Carlo M., Sabbioni, Silvia, Russo, Giandomenico, Negrini, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637322/
https://www.ncbi.nlm.nih.gov/pubmed/26090867

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