Neuroinflammation is not a Prerequisite for Diabetes-induced Tau Phosphorylation

Abnormal phosphorylation and aggregation of tau is a key hallmark of Alzheimer's disease (AD). AD is a multifactorial neurodegenerative disorder for which Diabetes Mellitus (DM) is a risk factor. In animal models for DM, the phosphorylation and aggregation of tau is induced or exacerbated, howe...

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Detalles Bibliográficos
Autores principales: van der Harg, Judith M., Eggels, Leslie, Ruigrok, Silvie R., Hoozemans, Jeroen J. M., la Fleur, Susanne E., Scheper, Wiep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637426/
https://www.ncbi.nlm.nih.gov/pubmed/26617484
http://dx.doi.org/10.3389/fnins.2015.00432

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