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New Insights in the Diagnosis and Treatment of Heart Failure
Cardiovascular disease is the leading cause of mortality in the US and in westernized countries with ischemic heart disease accounting for the majority of these deaths. Paradoxically, the improvements in the medical and surgical treatments of acute coronary syndrome are leading to an increasing numb...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637457/ https://www.ncbi.nlm.nih.gov/pubmed/26634204 http://dx.doi.org/10.1155/2015/265260 |
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author | Agnetti, Giulio Piepoli, Massimo F. Siniscalchi, Giuseppe Nicolini, Francesco |
author_facet | Agnetti, Giulio Piepoli, Massimo F. Siniscalchi, Giuseppe Nicolini, Francesco |
author_sort | Agnetti, Giulio |
collection | PubMed |
description | Cardiovascular disease is the leading cause of mortality in the US and in westernized countries with ischemic heart disease accounting for the majority of these deaths. Paradoxically, the improvements in the medical and surgical treatments of acute coronary syndrome are leading to an increasing number of “survivors” who are then developing heart failure. Despite considerable advances in its management, the gold standard for the treatment of end-stage heart failure patients remains heart transplantation. Nevertheless, this procedure can be offered only to a small percentage of patients who could benefit from a new heart due to the limited availability of donor organs. The aim of this review is to evaluate the safety and efficacy of innovative approaches in the diagnosis and treatment of patients refractory to standard medical therapy and excluded from cardiac transplantation lists. |
format | Online Article Text |
id | pubmed-4637457 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-46374572015-12-02 New Insights in the Diagnosis and Treatment of Heart Failure Agnetti, Giulio Piepoli, Massimo F. Siniscalchi, Giuseppe Nicolini, Francesco Biomed Res Int Review Article Cardiovascular disease is the leading cause of mortality in the US and in westernized countries with ischemic heart disease accounting for the majority of these deaths. Paradoxically, the improvements in the medical and surgical treatments of acute coronary syndrome are leading to an increasing number of “survivors” who are then developing heart failure. Despite considerable advances in its management, the gold standard for the treatment of end-stage heart failure patients remains heart transplantation. Nevertheless, this procedure can be offered only to a small percentage of patients who could benefit from a new heart due to the limited availability of donor organs. The aim of this review is to evaluate the safety and efficacy of innovative approaches in the diagnosis and treatment of patients refractory to standard medical therapy and excluded from cardiac transplantation lists. Hindawi Publishing Corporation 2015 2015-10-26 /pmc/articles/PMC4637457/ /pubmed/26634204 http://dx.doi.org/10.1155/2015/265260 Text en Copyright © 2015 Giulio Agnetti et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Agnetti, Giulio Piepoli, Massimo F. Siniscalchi, Giuseppe Nicolini, Francesco New Insights in the Diagnosis and Treatment of Heart Failure |
title | New Insights in the Diagnosis and Treatment of Heart Failure |
title_full | New Insights in the Diagnosis and Treatment of Heart Failure |
title_fullStr | New Insights in the Diagnosis and Treatment of Heart Failure |
title_full_unstemmed | New Insights in the Diagnosis and Treatment of Heart Failure |
title_short | New Insights in the Diagnosis and Treatment of Heart Failure |
title_sort | new insights in the diagnosis and treatment of heart failure |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637457/ https://www.ncbi.nlm.nih.gov/pubmed/26634204 http://dx.doi.org/10.1155/2015/265260 |
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