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Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh

The aim of the current study was to evaluate microbial contamination in terms of microbial load (total aerobic count and total coliform count) and specific pathogenic bacteria (Salmonella spp., Escherichia coli, particularly Escherichia coli 0157) in thirteen antidiabetic herbal preparations (ADHPs)...

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Detalles Bibliográficos
Autores principales: Zamir, Rausan, Hosen, Anowar, Ullah, M. Obayed, Nahar, Nilufar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637483/
https://www.ncbi.nlm.nih.gov/pubmed/26587044
http://dx.doi.org/10.1155/2015/243593
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author Zamir, Rausan
Hosen, Anowar
Ullah, M. Obayed
Nahar, Nilufar
author_facet Zamir, Rausan
Hosen, Anowar
Ullah, M. Obayed
Nahar, Nilufar
author_sort Zamir, Rausan
collection PubMed
description The aim of the current study was to evaluate microbial contamination in terms of microbial load (total aerobic count and total coliform count) and specific pathogenic bacteria (Salmonella spp., Escherichia coli, particularly Escherichia coli 0157) in thirteen antidiabetic herbal preparations (ADHPs) from Dhaka City. All the thirteen ADHPs had been found contaminated with fungi and different pathogenic bacteria. From the data, it is found that only two of these preparations (ADHP-1 and ADHP-12) complied with the safety limit (as stated in different Pharmacopoeias and WHO guidelines) evaluated by all different microbial counts. None of these herbal preparations could assure the safety as all of them were contaminated by fungi. The overall safety regarding heavy metal content (Zn, Cu, Mn, Cr, Cd, and Pb) was assured as none of them exceeded the safety limit of the daily intake. Microbial contaminants in these herbal preparations pose a potential risk for human health and care should be taken in every step involved in the preparation of these herbal preparations to assure safety.
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spelling pubmed-46374832015-11-19 Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh Zamir, Rausan Hosen, Anowar Ullah, M. Obayed Nahar, Nilufar Evid Based Complement Alternat Med Research Article The aim of the current study was to evaluate microbial contamination in terms of microbial load (total aerobic count and total coliform count) and specific pathogenic bacteria (Salmonella spp., Escherichia coli, particularly Escherichia coli 0157) in thirteen antidiabetic herbal preparations (ADHPs) from Dhaka City. All the thirteen ADHPs had been found contaminated with fungi and different pathogenic bacteria. From the data, it is found that only two of these preparations (ADHP-1 and ADHP-12) complied with the safety limit (as stated in different Pharmacopoeias and WHO guidelines) evaluated by all different microbial counts. None of these herbal preparations could assure the safety as all of them were contaminated by fungi. The overall safety regarding heavy metal content (Zn, Cu, Mn, Cr, Cd, and Pb) was assured as none of them exceeded the safety limit of the daily intake. Microbial contaminants in these herbal preparations pose a potential risk for human health and care should be taken in every step involved in the preparation of these herbal preparations to assure safety. Hindawi Publishing Corporation 2015 2015-10-26 /pmc/articles/PMC4637483/ /pubmed/26587044 http://dx.doi.org/10.1155/2015/243593 Text en Copyright © 2015 Rausan Zamir et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zamir, Rausan
Hosen, Anowar
Ullah, M. Obayed
Nahar, Nilufar
Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh
title Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh
title_full Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh
title_fullStr Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh
title_full_unstemmed Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh
title_short Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh
title_sort microbial and heavy metal contaminant of antidiabetic herbal preparations formulated in bangladesh
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637483/
https://www.ncbi.nlm.nih.gov/pubmed/26587044
http://dx.doi.org/10.1155/2015/243593
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