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Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh
The aim of the current study was to evaluate microbial contamination in terms of microbial load (total aerobic count and total coliform count) and specific pathogenic bacteria (Salmonella spp., Escherichia coli, particularly Escherichia coli 0157) in thirteen antidiabetic herbal preparations (ADHPs)...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637483/ https://www.ncbi.nlm.nih.gov/pubmed/26587044 http://dx.doi.org/10.1155/2015/243593 |
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author | Zamir, Rausan Hosen, Anowar Ullah, M. Obayed Nahar, Nilufar |
author_facet | Zamir, Rausan Hosen, Anowar Ullah, M. Obayed Nahar, Nilufar |
author_sort | Zamir, Rausan |
collection | PubMed |
description | The aim of the current study was to evaluate microbial contamination in terms of microbial load (total aerobic count and total coliform count) and specific pathogenic bacteria (Salmonella spp., Escherichia coli, particularly Escherichia coli 0157) in thirteen antidiabetic herbal preparations (ADHPs) from Dhaka City. All the thirteen ADHPs had been found contaminated with fungi and different pathogenic bacteria. From the data, it is found that only two of these preparations (ADHP-1 and ADHP-12) complied with the safety limit (as stated in different Pharmacopoeias and WHO guidelines) evaluated by all different microbial counts. None of these herbal preparations could assure the safety as all of them were contaminated by fungi. The overall safety regarding heavy metal content (Zn, Cu, Mn, Cr, Cd, and Pb) was assured as none of them exceeded the safety limit of the daily intake. Microbial contaminants in these herbal preparations pose a potential risk for human health and care should be taken in every step involved in the preparation of these herbal preparations to assure safety. |
format | Online Article Text |
id | pubmed-4637483 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-46374832015-11-19 Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh Zamir, Rausan Hosen, Anowar Ullah, M. Obayed Nahar, Nilufar Evid Based Complement Alternat Med Research Article The aim of the current study was to evaluate microbial contamination in terms of microbial load (total aerobic count and total coliform count) and specific pathogenic bacteria (Salmonella spp., Escherichia coli, particularly Escherichia coli 0157) in thirteen antidiabetic herbal preparations (ADHPs) from Dhaka City. All the thirteen ADHPs had been found contaminated with fungi and different pathogenic bacteria. From the data, it is found that only two of these preparations (ADHP-1 and ADHP-12) complied with the safety limit (as stated in different Pharmacopoeias and WHO guidelines) evaluated by all different microbial counts. None of these herbal preparations could assure the safety as all of them were contaminated by fungi. The overall safety regarding heavy metal content (Zn, Cu, Mn, Cr, Cd, and Pb) was assured as none of them exceeded the safety limit of the daily intake. Microbial contaminants in these herbal preparations pose a potential risk for human health and care should be taken in every step involved in the preparation of these herbal preparations to assure safety. Hindawi Publishing Corporation 2015 2015-10-26 /pmc/articles/PMC4637483/ /pubmed/26587044 http://dx.doi.org/10.1155/2015/243593 Text en Copyright © 2015 Rausan Zamir et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Zamir, Rausan Hosen, Anowar Ullah, M. Obayed Nahar, Nilufar Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh |
title | Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh |
title_full | Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh |
title_fullStr | Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh |
title_full_unstemmed | Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh |
title_short | Microbial and Heavy Metal Contaminant of Antidiabetic Herbal Preparations Formulated in Bangladesh |
title_sort | microbial and heavy metal contaminant of antidiabetic herbal preparations formulated in bangladesh |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637483/ https://www.ncbi.nlm.nih.gov/pubmed/26587044 http://dx.doi.org/10.1155/2015/243593 |
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