Squamous Cell Carcinoma of the Renal Pelvis as a Result of Long-Standing Staghorn Calculi

We report on a 79-year-old woman with staghorn calculi who presented with severe hypercalcemia. She was later found to have humoral hypercalcemia of malignancy caused by a rare tumor, squamous cell carcinoma of the renal pelvis. Chronic irritation, infection and inflammation from staghorn stones cau...

Descripción completa

Detalles Bibliográficos
Autores principales: Jongyotha, Kamonchanok, Sriphrapradang, Chutintorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2015
Materias:
Published online: October 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637796/
https://www.ncbi.nlm.nih.gov/pubmed/26557077
http://dx.doi.org/10.1159/000440764
_version_ 1782399832169644032
author Jongyotha, Kamonchanok
Sriphrapradang, Chutintorn
author_facet Jongyotha, Kamonchanok
Sriphrapradang, Chutintorn
author_sort Jongyotha, Kamonchanok
collection PubMed
description We report on a 79-year-old woman with staghorn calculi who presented with severe hypercalcemia. She was later found to have humoral hypercalcemia of malignancy caused by a rare tumor, squamous cell carcinoma of the renal pelvis. Chronic irritation, infection and inflammation from staghorn stones cause squamous metaplasia, leading to squamous cell carcinoma of the renal collecting system. The prognosis is very poor, with a 5-year survival rate of <10%. This case highlights the importance of awareness of a very rare and aggressive carcinoma in a patient with long-standing nephrolithiasis.
format Online
Article
Text
id pubmed-4637796
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher S. Karger AG
record_format MEDLINE/PubMed
spelling pubmed-46377962015-11-09 Squamous Cell Carcinoma of the Renal Pelvis as a Result of Long-Standing Staghorn Calculi Jongyotha, Kamonchanok Sriphrapradang, Chutintorn Case Rep Oncol Published online: October 2015 We report on a 79-year-old woman with staghorn calculi who presented with severe hypercalcemia. She was later found to have humoral hypercalcemia of malignancy caused by a rare tumor, squamous cell carcinoma of the renal pelvis. Chronic irritation, infection and inflammation from staghorn stones cause squamous metaplasia, leading to squamous cell carcinoma of the renal collecting system. The prognosis is very poor, with a 5-year survival rate of <10%. This case highlights the importance of awareness of a very rare and aggressive carcinoma in a patient with long-standing nephrolithiasis. S. Karger AG 2015-10-03 /pmc/articles/PMC4637796/ /pubmed/26557077 http://dx.doi.org/10.1159/000440764 Text en Copyright © 2015 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Published online: October 2015
Jongyotha, Kamonchanok
Sriphrapradang, Chutintorn
Squamous Cell Carcinoma of the Renal Pelvis as a Result of Long-Standing Staghorn Calculi
title Squamous Cell Carcinoma of the Renal Pelvis as a Result of Long-Standing Staghorn Calculi
title_full Squamous Cell Carcinoma of the Renal Pelvis as a Result of Long-Standing Staghorn Calculi
title_fullStr Squamous Cell Carcinoma of the Renal Pelvis as a Result of Long-Standing Staghorn Calculi
title_full_unstemmed Squamous Cell Carcinoma of the Renal Pelvis as a Result of Long-Standing Staghorn Calculi
title_short Squamous Cell Carcinoma of the Renal Pelvis as a Result of Long-Standing Staghorn Calculi
title_sort squamous cell carcinoma of the renal pelvis as a result of long-standing staghorn calculi
topic Published online: October 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637796/
https://www.ncbi.nlm.nih.gov/pubmed/26557077
http://dx.doi.org/10.1159/000440764
work_keys_str_mv AT jongyothakamonchanok squamouscellcarcinomaoftherenalpelvisasaresultoflongstandingstaghorncalculi
AT sriphrapradangchutintorn squamouscellcarcinomaoftherenalpelvisasaresultoflongstandingstaghorncalculi

Ejemplares similares