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An EGFR/Src-dependent β4 integrin/FAK complex contributes to malignancy of breast cancer

β4 integrin and focal adhesion kinase (FAK) are often associated with a poor prognosis in cancer patients, and their signaling events have recently been linked to malignant outcomes. Here, we demonstrate, for the first time, physical and functional interactions between β4 integrin and FAK that influ...

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Detalles Bibliográficos
Autores principales: Tai, Yu-Ling, Chu, Pei-Yu, Lai, I-Rue, Wang, Ming-Yang, Tseng, Hui-Yuan, Guan, Jun-Lin, Liou, Jun-Yang, Shen, Tang-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637903/
https://www.ncbi.nlm.nih.gov/pubmed/26549523
http://dx.doi.org/10.1038/srep16408