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FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7

Cancer-associated fibroblasts (CAFs), as the activated fibroblasts in the tumor stroma, are important modifiers of tumour progression. In the present study, we observed that azoxymethane and dextran sodium sulfate treatments induced increasingly severe colorectal mucosal inflammation and the intratu...

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Detalles Bibliográficos
Autores principales: Bai, Yu-Pan, Shang, Kun, Chen, Huan, Ding, Fei, Wang, Zhen, Liang, Chen, Xu, Ye, Sun, Meng-Hong, LI, Ying-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637995/
https://www.ncbi.nlm.nih.gov/pubmed/26183471
http://dx.doi.org/10.1111/cas.12745