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Induced pluripotent stem cell technology for dissecting the cancer epigenome
Cancer arises through the accumulation of both genetic and epigenetic alterations. Although the causal role of genetic mutations on cancer development has been established in vivo, similar evidence for epigenetic alterations is limited. Moreover, mutual interactions between genetic mutations and epi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley & Sons, Ltd
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638022/ https://www.ncbi.nlm.nih.gov/pubmed/26224327 http://dx.doi.org/10.1111/cas.12758 |