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Protein–Protein Interactions Modulate the Docking-Dependent E3-Ubiquitin Ligase Activity of Carboxy-Terminus of Hsc70-Interacting Protein (CHIP)

CHIP is a tetratricopeptide repeat (TPR) domain protein that functions as an E3-ubiquitin ligase. As well as linking the molecular chaperones to the ubiquitin proteasome system, CHIP also has a docking-dependent mode where it ubiquitinates native substrates, thereby regulating their steady state lev...

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Detalles Bibliográficos
Autores principales:	Narayan, Vikram, Landré, Vivien, Ning, Jia, Hernychova, Lenka, Muller, Petr, Verma, Chandra, Walkinshaw, Malcolm D., Blackburn, Elizabeth A., Ball, Kathryn L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638040/ https://www.ncbi.nlm.nih.gov/pubmed/26330542 http://dx.doi.org/10.1074/mcp.M115.051169

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