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Determining the origin of synchronous multifocal bladder cancer by exome sequencing

BACKGROUND: Synchronous multifocal tumours are commonly observed in urothelial carcinomas of the bladder. The origin of these physically independent tumours has been proposed to occur by either intraluminal migration (clonal) or spontaneous transformation of multiple cells by carcinogens (field effe...

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Detalles Bibliográficos
Autores principales: Acar, Ömer, Özkurt, Ezgi, Demir, Gulfem, Saraç, Hilal, Alkan, Can, Esen, Tarık, Somel, Mehmet, Lack, Nathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638097/
https://www.ncbi.nlm.nih.gov/pubmed/26553077
http://dx.doi.org/10.1186/s12885-015-1859-8