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Diversity of CRISPR-Cas immune systems and molecular machines
Bacterial adaptive immunity hinges on CRISPR-Cas systems that provide DNA-encoded, RNA-mediated targeting of exogenous nucleic acids. A plethora of CRISPR molecular machines occur broadly in prokaryotic genomes, with a diversity of Cas nucleases that can be repurposed for various applications.
Autor principal: | Barrangou, Rodolphe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638107/ https://www.ncbi.nlm.nih.gov/pubmed/26549499 http://dx.doi.org/10.1186/s13059-015-0816-9 |
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