Cargando…

A Membrane-Type-1 Matrix Metalloproteinase (MT1-MMP) – Discoidin Domain Receptor 1 Axis Regulates Collagen-Induced Apoptosis in Breast Cancer Cells

During tumour dissemination, invading breast carcinoma cells become confronted with a reactive stroma, a type I collagen-rich environment endowed with anti-proliferative and pro-apoptotic properties. To develop metastatic capabilities, tumour cells must acquire the capacity to cope with this novel m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Assent, Delphine, Bourgot, Isabelle, Hennuy, Benoît, Geurts, Pierre, Noël, Agnès, Foidart, Jean-Michel, Maquoi, Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638154/ https://www.ncbi.nlm.nih.gov/pubmed/25774665 http://dx.doi.org/10.1371/journal.pone.0116006

Ejemplares similares

Reciprocal Interplay Between Fibrillar Collagens and Collagen-Binding Integrins: Implications in Cancer Progression and Metastasis
por: Bourgot, Isabelle, et al.
Publicado: (2020)

Collagen and Discoidin Domain Receptor 1 Partnership: A Multifaceted Role in the Regulation of Breast Carcinoma Cell Phenotype
por: Saby, Charles, et al.
Publicado: (2021)

MT4-MMP: The GPI-Anchored Membrane-Type Matrix Metalloprotease with Multiple Functions in Diseases
por: Yip, Cassandre, et al.
Publicado: (2019)

High threshold of β1 integrin inhibition required to block collagen I-induced membrane type-1 matrix metalloproteinase (MT1-MMP) activation of matrix metalloproteinase 2 (MMP-2)
por: Borrirukwanit, Kulrut, et al.
Publicado: (2014)

Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
por: Hur, J. H., et al.
Publicado: (2000)

Dynamic Expression of Membrane Type 1-Matrix Metalloproteinase (Mt1-mmp/Mmp14) in the Mouse Embryo
por: Muñoz-Sáez, Emma, et al.
Publicado: (2021)

Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts
por: Majkowska, Iwona, et al.
Publicado: (2017)

Analysis of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP, MMP14) in Eutopic and Ectopic Endometrium and in Serum and Endocervical Mucus of Endometriosis
por: Maoga, Jane B., et al.
Publicado: (2023)

Membrane-type 4 matrix metalloproteinase (MT4-MMP) induces lung metastasis by alteration of primary breast tumour vascular architecture
por: Chabottaux, Vincent, et al.
Publicado: (2009)

DDR1 and MT1-MMP Expression Levels Are Determinant for Triggering BIK-Mediated Apoptosis by 3D Type I Collagen Matrix in Invasive Basal-Like Breast Carcinoma Cells
por: Saby, Charles, et al.
Publicado: (2019)

Remodelling of the fibre-aggregate structure of collagen gels by cancer-associated fibroblasts: A time-resolved grey-tone image analysis based on stochastic modelling
por: Gommes, Cedric J., et al.
Publicado: (2023)

Membrane-type I matrix metalloproteinase (MT1-MMP), lipid metabolism, and therapeutic implications
por: Xia, Xiao-Dan, et al.
Publicado: (2021)

Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity
por: Cerofolini, Linda, et al.
Publicado: (2016)

Metalloproteinase MT1-MMP islets act as memory devices for podosome reemergence
por: El Azzouzi, Karim, et al.
Publicado: (2016)

Regulation of MT1-MMP/MMP-2/TIMP-2 axis in human placenta
por: Vincent, Zoë L, et al.
Publicado: (2015)

Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas
por: Forsyth, P A, et al.
Publicado: (1999)

Matrix Metalloproteinases (MMPs) Regulate Fibrin-invasive Activity via MT1-MMP–dependent and –independent Processes
por: Hotary, Kevin B., et al.
Publicado: (2002)

Basal localization of MT1-MMP is essential for epithelial cell morphogenesis in 3D collagen matrix
por: Weaver, Sarah A., et al.
Publicado: (2014)

Cytoplasmic Tail of MT1-MMP: A Hub of MT1-MMP Regulation and Function
por: Strouhalova, Katerina, et al.
Publicado: (2023)

Developmental expression of membrane type 4-matrix metalloproteinase (Mt4-mmp/Mmp17) in the mouse embryo
por: Blanco, María José, et al.
Publicado: (2017)

Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP
por: Åhlén, Jan, et al.
Publicado: (2001)

Interactions between the discoidin domain receptor 1 and β1 integrin regulate attachment to collagen
por: Staudinger, Lisa A., et al.
Publicado: (2013)

Conversion of Stationary to Invasive Tumor Initiating Cells (TICs): Role of Hypoxia in Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) Trafficking
por: Li, Jian, et al.
Publicado: (2012)

The Oncogenic Response to MiR-335 Is Associated with Cell Surface Expression of Membrane-Type 1 Matrix Metalloproteinase (MT1-MMP) Activity
por: Rojas, Fausto, et al.
Publicado: (2015)

Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis
por: Remacle, Albert G, et al.
Publicado: (2016)

Serum Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) mRNA Protected by Exosomes as a Potential Biomarker for Gastric Cancer
por: Dong, Zhaogang, et al.
Publicado: (2019)

“Splitting the matrix”: intussusceptive angiogenesis meets MT1‐MMP
por: D'Amico, Gabriela, et al.
Publicado: (2019)

Type I collagen fibrils and discoidin domain receptor 1 set invadosomes straight
por: Moreau, Violaine, et al.
Publicado: (2015)

MT1-MMP recruits the ER-Golgi SNARE Bet1 for efficient MT1-MMP transport to the plasma membrane
por: Miyagawa, Takuya, et al.
Publicado: (2019)

Membrane-Type 4 Matrix Metalloproteinase (MT4-MMP) Modulates Water Homeostasis in Mice
por: Srichai, Manakan B., et al.
Publicado: (2011)

ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1)
por: Shitomi, Yasuyuki, et al.
Publicado: (2015)

The Catalytic Domain Mediates Homomultimerization of MT1-MMP and the Prodomain Interferes with MT1-MMP Oligomeric Complex Assembly
por: Fogarasi, Marton, et al.
Publicado: (2022)

The Regulation of Matrix Metalloproteinase Expression and the Role of Discoidin Domain Receptor 1/2 Signalling in Zoledronate-treated PC3 Cells
por: Reel, Buket, et al.
Publicado: (2015)

Collagen recognition and transmembrane signalling by discoidin domain receptors()
por: Carafoli, Federico, et al.
Publicado: (2013)

New and Paradoxical Roles of Matrix Metalloproteinases in the Tumor Microenvironment
por: Noël, Agnès, et al.
Publicado: (2012)

Ensnaring membrane type 1-matrix metalloproteinase (MT1-MMP) with tissue inhibitor of metalloproteinase (TIMP)-2 using the haemopexin domain of the protease as a carrier: a targeted approach in cancer inhibition
por: Jiang, Bingjie, et al.
Publicado: (2017)

MT1-MMP dependent repression of the tumor suppressor SPRY4 contributes to MT1-MMP driven melanoma cell motility
por: Shaverdashvili, Khvaramze, et al.
Publicado: (2015)

Crystallographic Insight into Collagen Recognition by Discoidin Domain Receptor 2
por: Carafoli, Federico, et al.
Publicado: (2009)

Collagen binding specificity of the discoidin domain receptors: Binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1
por: Xu, Huifang, et al.
Publicado: (2011)

An evaluation of matrix metalloproteinase-9 (Mmp-9) and tissue inhibitor metalloproteinase-1 (Timp-1) Serum levels and the Mmp-9/Timp-1 Ratio in Covid-19 patients
por: Demir, Nazlim Aktug, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_45dilolur234iuaiau1r3khadm