Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity

Human African trypanosomiasis (HAT), Chagas disease and leishmaniasis, which are caused by the trypanosomatids Trypanosoma brucei, Trypanosoma cruzi and Leishmania species, are among the most deadly neglected tropical diseases. The development of drugs that are active against several trypanosomatids...

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Detalles Bibliográficos
Autores principales: Di Pietro, Ornella, Vicente-García, Esther, Taylor, Martin C., Berenguer, Diana, Viayna, Elisabet, Lanzoni, Anna, Sola, Irene, Sayago, Helena, Riera, Cristina, Fisa, Roser, Clos, M. Victòria, Pérez, Belén, Kelly, John M., Lavilla, Rodolfo, Muñoz-Torrero, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editions Scientifiques Elsevier 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638191/
https://www.ncbi.nlm.nih.gov/pubmed/26479031
http://dx.doi.org/10.1016/j.ejmech.2015.10.007

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