Polymorphisms in the Promoters of the MMP-2 and TIMP-2 Genes Are Associated with Spontaneous Deep Intracerebral Hemorrhage in the Taiwan Population

BACKGROUND: Spontaneous intracerebral hemorrhage (ICH) is a devastating stroke subtype. Matrix metalloproteinases (MMPs) function in the degradation of extracellular matrix and the activities of MMPs are modulated by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). This...

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Detalles Bibliográficos
Autores principales: Chen, Yi Chun, Ho, Wei Min, Lee, Yun Shien, Chen, Huei Wen, Chen, Chiung-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638341/
https://www.ncbi.nlm.nih.gov/pubmed/26551785
http://dx.doi.org/10.1371/journal.pone.0142482

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