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Bacterial Exotoxins and the Inflammasome
The inflammasomes are intracellular protein complexes that play an important role in innate immune sensing. Activation of inflammasomes leads to activation of caspase-1 and maturation and secretion of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18. In certain myeloid cells, this activa...
Autores principales: | Greaney, Allison J., Leppla, Stephen H., Moayeri, Mahtab |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639612/ https://www.ncbi.nlm.nih.gov/pubmed/26617605 http://dx.doi.org/10.3389/fimmu.2015.00570 |
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