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Bacterial Exotoxins and the Inflammasome

The inflammasomes are intracellular protein complexes that play an important role in innate immune sensing. Activation of inflammasomes leads to activation of caspase-1 and maturation and secretion of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18. In certain myeloid cells, this activa...

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Detalles Bibliográficos
Autores principales: Greaney, Allison J., Leppla, Stephen H., Moayeri, Mahtab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639612/
https://www.ncbi.nlm.nih.gov/pubmed/26617605
http://dx.doi.org/10.3389/fimmu.2015.00570

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