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Uric acid enhances the antitumor immunity of dendritic cell-based vaccine

Uric acid (UA) released from dying cells has been recognized by the immune system as a danger signal. In response to UA, dendritic cells (DC) in the immune system mature and enhance the T cell response to foreign antigens. It is conceivable that the antitumor immunity of a tumor vaccine could be pro...

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Detalles Bibliográficos
Autores principales: Wang, Yihan, Ma, Xuelei, Su, Chao, Peng, Bin, Du, Jing, Jia, Hongyuan, Luo, Min, Fang, Chunju, Wei, Yuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639747/
https://www.ncbi.nlm.nih.gov/pubmed/26553557
http://dx.doi.org/10.1038/srep16427