A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds

Plasmodium falciparum gametocytes, specifically the mature stages, are the only malaria parasite stage in humans transmissible to the mosquito vector. Anti-malarial drugs capable of killing these forms are considered essential for the eradication of malaria and tools allowing the screening of large...

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Detalles Bibliográficos
Autores principales: Lucantoni, Leonardo, Silvestrini, Francesco, Signore, Michele, Siciliano, Giulia, Eldering, Maarten, Dechering, Koen J., Avery, Vicky M., Alano, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639769/
https://www.ncbi.nlm.nih.gov/pubmed/26553647
http://dx.doi.org/10.1038/srep16414

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