AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation

The phosphoinositide 3-kinase–Akt signaling pathway is essential to many biological processes, including cell proliferation, survival, metabolism, and angiogenesis, under pathophysiological conditions. Although 3-phosphoinositide–dependent kinase 1 (PDK1) is a primary activator of Akt at the plasma...

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Detalles Bibliográficos
Autores principales: Park, Hyojin, Lee, Sungwoon, Shrestha, Pravesh, Kim, Jihye, Park, Jeong Ae, Ko, Yeongrim, Ban, Young Ho, Park, Dae-Young, Ha, Sang-Jun, Koh, Gou Young, Hong, Victor Sukbong, Mochizuki, Naoki, Kim, Young-Myeong, Lee, Weontae, Kwon, Young-Guen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639856/
https://www.ncbi.nlm.nih.gov/pubmed/26553931
http://dx.doi.org/10.1083/jcb.201503113

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