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Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling

Notch family members are transmembrane receptors that mediate essential developmental programs. Upon ligand binding, a proteolytic event releases the intracellular domain of Notch, which translocates to the nucleus to regulate gene transcription. In addition, Notch trafficking across the endolysosom...

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Detalles Bibliográficos
Autores principales:	Li, Haiying, Koo, Yeon, Mao, Xicheng, Sifuentes-Dominguez, Luis, Morris, Lindsey L., Jia, Da, Miyata, Naoteru, Faulkner, Rebecca A., van Deursen, Jan M., Vooijs, Marc, Billadeau, Daniel D., van de Sluis, Bart, Cleaver, Ondine, Burstein, Ezra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639872/ https://www.ncbi.nlm.nih.gov/pubmed/26553930 http://dx.doi.org/10.1083/jcb.201505108

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