IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel

Metastatic tumour recurrence due to failed treatments remains a major challenge of breast cancer clinical management. Here we report that interleukin-1 receptor-associated kinase 1 (IRAK1) is overexpressed in a subset of breast cancers, in particular triple-negative breast cancer (TNBC), where it ac...

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Detalles Bibliográficos
Autores principales: Wee, Zhen Ning, Yatim, Siti Maryam J. M., Kohlbauer, Vera K, Feng, Min, Goh, Jian Yuan, Yi, Bao, Lee, Puay Leng, Zhang, Songjing, Wang, Pan Pan, Lim, Elgene, Tam, Wai Leong, Cai, Yu, Ditzel, Henrik J, Hoon, Dave S. B., Tan, Ern Yu, Yu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640083/
https://www.ncbi.nlm.nih.gov/pubmed/26503059
http://dx.doi.org/10.1038/ncomms9746

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