Dilp8 requires the neuronal relaxin receptor Lgr3 to couple growth to developmental timing

How different organs in the body sense growth perturbations in distant tissues to coordinate their size during development is poorly understood. Here we mutate an invertebrate orphan relaxin receptor gene, the Drosophila Leucine-rich repeat-containing G protein-coupled receptor 3 (Lgr3), and find bo...

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Detalles Bibliográficos
Autores principales: Garelli, Andres, Heredia, Fabiana, Casimiro, Andreia P., Macedo, Andre, Nunes, Catarina, Garcez, Marcia, Dias, Angela R. Mantas, Volonte, Yanel A., Uhlmann, Thomas, Caparros, Esther, Koyama, Takashi, Gontijo, Alisson M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640092/
https://www.ncbi.nlm.nih.gov/pubmed/26510564
http://dx.doi.org/10.1038/ncomms9732

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