Cargando…

Serotypes of group B streptococci in western Sweden and comparison with serotypes in two previous studies starting from 1988

BACKGROUND: Group B Streptococci (GBS) are the most common neonatal pathogens and infect immunocompromised and elderly individuals. The species has 10 different serotypes. Serotypes have been studied in the south-west area of Sweden in 1988–1997 and 1998–2001. The aim of this study was to study sero...

Descripción completa

Detalles Bibliográficos
Autores principales: Gudjónsdóttir, Margrét Johansson, Hentz, Elisabet, Berg, Stefan, Backhaus, Erik, Elfvin, Anders, Kawash, Samir, Trollfors, Birger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640215/
https://www.ncbi.nlm.nih.gov/pubmed/26553333
http://dx.doi.org/10.1186/s12879-015-1266-4
_version_ 1782400048333586432
author Gudjónsdóttir, Margrét Johansson
Hentz, Elisabet
Berg, Stefan
Backhaus, Erik
Elfvin, Anders
Kawash, Samir
Trollfors, Birger
author_facet Gudjónsdóttir, Margrét Johansson
Hentz, Elisabet
Berg, Stefan
Backhaus, Erik
Elfvin, Anders
Kawash, Samir
Trollfors, Birger
author_sort Gudjónsdóttir, Margrét Johansson
collection PubMed
description BACKGROUND: Group B Streptococci (GBS) are the most common neonatal pathogens and infect immunocompromised and elderly individuals. The species has 10 different serotypes. Serotypes have been studied in the south-west area of Sweden in 1988–1997 and 1998–2001. The aim of this study was to study serotypes in the same area from 2004 to 2009. METHODS: Invasive GBS isolates were collected prospectively from 2004 to 2009 in two counties in western Sweden with a population of 1.8 million, and were serotyped by latex agglutination. Clinical data were obtained from hospital records. During the study period 410 invasive GBS isolates from 398 patients were collected (multiple episodes ≥1 month apart). Clinical data were not available for two patients who are excluded. Four isolates were from stillborn neonates, 88 were from live born neonates and infants, and 318 from adults. RESULTS: Serotype III was the most common serotype (48 %) in neonates and infants followed by serotypes Ia (18 %) and V (16 %). In adults serotype V (39 %) dominated followed by serotypes III (20 %) and Ib (14 %). There was a significant increase of serotype V in comparison with the first study (1988–1997) but there were no significant changes in the serotype distribution between the present study and the second study (1998–2001). There were a few cases of serotype VI-IX, both in children and adults, not seen in the previous studies. Serotype V was more common among patients with arthritis than with any other manifestation. CONCLUSIONS: Changes in GBS serotypes occur over time in the same region, which must be considered when GBS vaccines are formulated.
format Online
Article
Text
id pubmed-4640215
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-46402152015-11-11 Serotypes of group B streptococci in western Sweden and comparison with serotypes in two previous studies starting from 1988 Gudjónsdóttir, Margrét Johansson Hentz, Elisabet Berg, Stefan Backhaus, Erik Elfvin, Anders Kawash, Samir Trollfors, Birger BMC Infect Dis Research Article BACKGROUND: Group B Streptococci (GBS) are the most common neonatal pathogens and infect immunocompromised and elderly individuals. The species has 10 different serotypes. Serotypes have been studied in the south-west area of Sweden in 1988–1997 and 1998–2001. The aim of this study was to study serotypes in the same area from 2004 to 2009. METHODS: Invasive GBS isolates were collected prospectively from 2004 to 2009 in two counties in western Sweden with a population of 1.8 million, and were serotyped by latex agglutination. Clinical data were obtained from hospital records. During the study period 410 invasive GBS isolates from 398 patients were collected (multiple episodes ≥1 month apart). Clinical data were not available for two patients who are excluded. Four isolates were from stillborn neonates, 88 were from live born neonates and infants, and 318 from adults. RESULTS: Serotype III was the most common serotype (48 %) in neonates and infants followed by serotypes Ia (18 %) and V (16 %). In adults serotype V (39 %) dominated followed by serotypes III (20 %) and Ib (14 %). There was a significant increase of serotype V in comparison with the first study (1988–1997) but there were no significant changes in the serotype distribution between the present study and the second study (1998–2001). There were a few cases of serotype VI-IX, both in children and adults, not seen in the previous studies. Serotype V was more common among patients with arthritis than with any other manifestation. CONCLUSIONS: Changes in GBS serotypes occur over time in the same region, which must be considered when GBS vaccines are formulated. BioMed Central 2015-11-09 /pmc/articles/PMC4640215/ /pubmed/26553333 http://dx.doi.org/10.1186/s12879-015-1266-4 Text en © Gudjónsdóttir et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Gudjónsdóttir, Margrét Johansson
Hentz, Elisabet
Berg, Stefan
Backhaus, Erik
Elfvin, Anders
Kawash, Samir
Trollfors, Birger
Serotypes of group B streptococci in western Sweden and comparison with serotypes in two previous studies starting from 1988
title Serotypes of group B streptococci in western Sweden and comparison with serotypes in two previous studies starting from 1988
title_full Serotypes of group B streptococci in western Sweden and comparison with serotypes in two previous studies starting from 1988
title_fullStr Serotypes of group B streptococci in western Sweden and comparison with serotypes in two previous studies starting from 1988
title_full_unstemmed Serotypes of group B streptococci in western Sweden and comparison with serotypes in two previous studies starting from 1988
title_short Serotypes of group B streptococci in western Sweden and comparison with serotypes in two previous studies starting from 1988
title_sort serotypes of group b streptococci in western sweden and comparison with serotypes in two previous studies starting from 1988
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640215/
https://www.ncbi.nlm.nih.gov/pubmed/26553333
http://dx.doi.org/10.1186/s12879-015-1266-4
work_keys_str_mv AT gudjonsdottirmargretjohansson serotypesofgroupbstreptococciinwesternswedenandcomparisonwithserotypesintwopreviousstudiesstartingfrom1988
AT hentzelisabet serotypesofgroupbstreptococciinwesternswedenandcomparisonwithserotypesintwopreviousstudiesstartingfrom1988
AT bergstefan serotypesofgroupbstreptococciinwesternswedenandcomparisonwithserotypesintwopreviousstudiesstartingfrom1988
AT backhauserik serotypesofgroupbstreptococciinwesternswedenandcomparisonwithserotypesintwopreviousstudiesstartingfrom1988
AT elfvinanders serotypesofgroupbstreptococciinwesternswedenandcomparisonwithserotypesintwopreviousstudiesstartingfrom1988
AT kawashsamir serotypesofgroupbstreptococciinwesternswedenandcomparisonwithserotypesintwopreviousstudiesstartingfrom1988
AT trollforsbirger serotypesofgroupbstreptococciinwesternswedenandcomparisonwithserotypesintwopreviousstudiesstartingfrom1988