Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis

BACKGROUND: Cyclin-dependent protein kinase-5 (CDK5) is an unusual member of the CDK family as it is not cell cycle regulated. However many of its substrates have roles in cell growth and oncogenesis, raising the possibility that CDK5 modulation could have therapeutic benefit. In order to establish...

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Detalles Bibliográficos
Autores principales: Grant, Nicola J., Coates, Philip J., Woods, Yvonne L., Bray, Susan E., Morrice, Nicholas A., Hastie, C. James, Lamont, Douglas J., Carey, Francis A., Sutherland, Calum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640224/
https://www.ncbi.nlm.nih.gov/pubmed/26555036
http://dx.doi.org/10.1186/s12885-015-1691-1

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