High glucose induces renal tubular epithelial injury via Sirt1/NF-kappaB/microR-29/Keap1 signal pathway

OBJECTIVE: Diabetic nephropathy (DN) is a serious complication that commonly confronted by diabetic patients. A common theory for the pathogenesis of this renal dysfunction in diabetes is cell injury, inflammation as well as oxidative stress. In this content, the detailed molecular mechanism underly...

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Detalles Bibliográficos
Autores principales: Zhou, Ling, Xu, De-yu, Sha, Wen-gang, Shen, Lei, Lu, Guo-yuan, Yin, Xia, Wang, Ming-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640239/
https://www.ncbi.nlm.nih.gov/pubmed/26552447
http://dx.doi.org/10.1186/s12967-015-0710-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640239/
https://www.ncbi.nlm.nih.gov/pubmed/26552447
http://dx.doi.org/10.1186/s12967-015-0710-y

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