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Pop in, pop out: a novel gene-targeting strategy for use with CRISPR-Cas9
The CRISPR-Cas9 system is frequently used to create small deletions in the genomes of mammalian cells, but the isolation of precisely targeted mutants is still challenging. A new, two-step ‘pop in & out’ targeting approach facilitates this task. See related Research article: http://www.genomebio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640370/ https://www.ncbi.nlm.nih.gov/pubmed/26553112 http://dx.doi.org/10.1186/s13059-015-0810-2 |