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Microenvironmental effects limit efficacy of thymoquinone treatment in a mouse model of ovarian cancer

BACKGROUND: Ovarian cancer is the most lethal gynecologic malignancy, with limited treatment options for chemoresistant disease. An important link between inflammation and peritoneal spread of ovarian cancer is NF-κB signaling. Thymoquinone (TQ) exerts multiple anti-tumorigenic cellular effects, inc...

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Detalles Bibliográficos
Autores principales:	Wilson, Andrew J., Saskowski, Jeanette, Barham, Whitney, Khabele, Dineo, Yull, Fiona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640396/ https://www.ncbi.nlm.nih.gov/pubmed/26552746 http://dx.doi.org/10.1186/s12943-015-0463-5

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