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HTLV-1 drives vigorous clonal expansion of infected CD8(+) T cells in natural infection

BACKGROUND: Human T-lymphotropic Virus Type I (HTLV-1) is a retrovirus that persistently infects 5–10 million individuals worldwide and causes disabling or fatal inflammatory and malignant diseases. The majority of the HTLV-1 proviral load is found in CD4(+) T cells, and the phenotype of adult T cel...

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Detalles Bibliográficos
Autores principales:	Melamed, Anat, Laydon, Daniel J., Al Khatib, Hebah, Rowan, Aileen G., Taylor, Graham P., Bangham, Charles R. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640420/ https://www.ncbi.nlm.nih.gov/pubmed/26552867 http://dx.doi.org/10.1186/s12977-015-0221-1

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