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A Temporal Window for Signal Activation Dictates the Dimensions of a Nodal Signaling Domain

Morphogen signaling is critical for the growth and patterning of tissues in embryos and adults, but how morphogen signaling gradients are generated in tissues remains controversial. The morphogen Nodal was proposed to form a long-range signaling gradient via a reaction-diffusion system, on the basis...

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Detalles Bibliográficos
Autores principales: van Boxtel, Antonius L., Chesebro, John E., Heliot, Claire, Ramel, Marie-Christine, Stone, Richard K., Hill, Caroline S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640439/
https://www.ncbi.nlm.nih.gov/pubmed/26506307
http://dx.doi.org/10.1016/j.devcel.2015.09.014