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Improving Multi-Epitope Long Peptide Vaccine Potency by Using a Strategy that Enhances CD4+ T Help in BALB/c Mice

Peptide-based vaccines are attractive approaches for cancer immunotherapy; but the success of these vaccines in clinical trials have been limited. Our goal is to improve immune responses and anti-tumor effects against a synthetic, multi-epitope, long peptide from rat Her2/neu (rHer2/neu) using the h...

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Detalles Bibliográficos
Autores principales: Ghaffari-Nazari, Haniyeh, Tavakkol-Afshari, Jalil, Jaafari, Mahmoud Reza, Tahaghoghi-Hajghorbani, Sahar, Masoumi, Elham, Jalali, Seyed Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640540/
https://www.ncbi.nlm.nih.gov/pubmed/26556756
http://dx.doi.org/10.1371/journal.pone.0142563