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The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29Q
Familial hypertrophic cardiomyopathy (FHC) is characterized by severe abnormal cardiac muscle growth. The traditional view of disease progression in FHC is that an increase in the Ca(2 +)-sensitivity of cardiac muscle contraction ultimately leads to pathogenic myocardial remodeling, though recent st...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640586/ https://www.ncbi.nlm.nih.gov/pubmed/26341255 http://dx.doi.org/10.1016/j.yjmcc.2015.08.017 |