Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis

Telomerase is typically expressed in cellular populations capable of extended replication, such as germ cells, tumor cells, and stem cells, but is also induced in tissue injury, repair and fibrosis. Its catalytic component, telomerase reverse transcriptase (TERT) is induced in lung fibroblasts from...

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Detalles Bibliográficos
Autores principales: Liu, Tianju, Yu, Hongfeng, Ding, Lin, Wu, Zhe, Gonzalez De Los Santos, Francina, Liu, Jianhua, Ullenbruch, Matthew, Hu, Biao, Martins, Vanessa, Phan, Sem H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640706/
https://www.ncbi.nlm.nih.gov/pubmed/26555817
http://dx.doi.org/10.1371/journal.pone.0142547

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