Progression of Alport Kidney Disease in Col4a3 Knock Out Mice Is Independent of Sex or Macrophage Depletion by Clodronate Treatment

Alport syndrome is a genetic disease of collagen IV (α3, 4, 5) resulting in renal failure. This study was designed to investigate sex-phenotype correlations and evaluate the contribution of macrophage infiltration to disease progression using Col4a3 knock out (Col4a3KO) mice, an established genetic...

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Detalles Bibliográficos
Autores principales: Kim, Munkyung, Piaia, Alessandro, Shenoy, Neeta, Kagan, David, Gapp, Berangere, Kueng, Benjamin, Weber, Delphine, Dietrich, William, Ksiazek, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640715/
https://www.ncbi.nlm.nih.gov/pubmed/26555339
http://dx.doi.org/10.1371/journal.pone.0141231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640715/
https://www.ncbi.nlm.nih.gov/pubmed/26555339
http://dx.doi.org/10.1371/journal.pone.0141231

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