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Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation

The pharmacological effect of opioids originates, at the cellular level, by their interaction with the μ-opioid receptor (mOR) resulting in the regulation of voltage-gated Ca(2+) channels and inwardly rectifying K(+) channels that ultimately modulate the synaptic transmission. Recently, an alternati...

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Detalles Bibliográficos
Autores principales:	Convertino, Marino, Samoshkin, Alexander, Viet, Chi T., Gauthier, Josee, Li Fraine, Steven P., Sharif-Naeini, Reza, Schmidt, Brian L., Maixner, William, Diatchenko, Luda, Dokholyan, Nikolay V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640872/ https://www.ncbi.nlm.nih.gov/pubmed/26554831 http://dx.doi.org/10.1371/journal.pone.0142826

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