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Effects of Etomidate on the Steroidogenesis of Rat Immature Leydig Cells

BACKGROUND: Etomidate is a rapid hypnotic intravenous anesthetic agent. The major side effect of etomidate is the reduced plasma concentration of corticosteroids, leading to the abnormal reaction of adrenals. Cortisol and testosterone biosynthesis has similar biosynthetic pathway, and shares several...

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Detalles Bibliográficos
Autores principales: Liu, Hua-Cheng, Zhu, Danyan, Wang, Chan, Guan, Hongguo, Li, Senlin, Hu, Cong, Chen, Zhichuan, Hu, Yuanyuan, Lin, Han, Lian, Qing-Quan, Ge, Ren-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640886/
https://www.ncbi.nlm.nih.gov/pubmed/26555702
http://dx.doi.org/10.1371/journal.pone.0139311