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Langerhans Cells Facilitate UVB-induced Epidermal Carcinogenesis

Ultraviolet B (UVB) light is considered the major environmental inducer of human keratinocyte DNA mutations, including within the tumor-suppressor gene p53, and chronic exposure is associated with cutaneous squamous cell carcinoma (SCC) formation. Langerhans cells (LC) comprise a dendritic network w...

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Detalles Bibliográficos
Autores principales:	Lewis, Julia M., Bürgler, Christina D., Freudzon, Marianna, Golubets, Kseniya, Gibson, Juliet F., Filler, Renata B., Girardi, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640962/ https://www.ncbi.nlm.nih.gov/pubmed/26053049 http://dx.doi.org/10.1038/jid.2015.207

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