CYR61/CCN1: A novel mediator of epidermal hyperplasia and inflammation in psoriasis?

The complex pathogenesis of psoriasis is still not fully understood. The study by Sun et al. (Sun et al., 2015) in this issue of the journal suggests that CYR61(now named CCN1), a secreted matricellular protein, plays a role in the pathogenesis of psoriasis, and thus targeting CCN1 represents a pote...

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Detalles Bibliográficos
Autores principales: Quan, Taihao, Johnston, Andrew, Gudjonsson, Johann, Fisher, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641044/
https://www.ncbi.nlm.nih.gov/pubmed/26548486
http://dx.doi.org/10.1038/jid.2015.300
Descripción
Sumario:The complex pathogenesis of psoriasis is still not fully understood. The study by Sun et al. (Sun et al., 2015) in this issue of the journal suggests that CYR61(now named CCN1), a secreted matricellular protein, plays a role in the pathogenesis of psoriasis, and thus targeting CCN1 represents a potential therapeutic strategy in its treatment.

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