CYR61/CCN1: A novel mediator of epidermal hyperplasia and inflammation in psoriasis?

The complex pathogenesis of psoriasis is still not fully understood. The study by Sun et al. (Sun et al., 2015) in this issue of the journal suggests that CYR61(now named CCN1), a secreted matricellular protein, plays a role in the pathogenesis of psoriasis, and thus targeting CCN1 represents a pote...

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Autores principales: Quan, Taihao, Johnston, Andrew, Gudjonsson, Johann, Fisher, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641044/
https://www.ncbi.nlm.nih.gov/pubmed/26548486
http://dx.doi.org/10.1038/jid.2015.300
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author Quan, Taihao
Johnston, Andrew
Gudjonsson, Johann
Fisher, Gary J.
author_facet Quan, Taihao
Johnston, Andrew
Gudjonsson, Johann
Fisher, Gary J.
author_sort Quan, Taihao
collection PubMed
description The complex pathogenesis of psoriasis is still not fully understood. The study by Sun et al. (Sun et al., 2015) in this issue of the journal suggests that CYR61(now named CCN1), a secreted matricellular protein, plays a role in the pathogenesis of psoriasis, and thus targeting CCN1 represents a potential therapeutic strategy in its treatment.
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spelling pubmed-46410442016-05-01 CYR61/CCN1: A novel mediator of epidermal hyperplasia and inflammation in psoriasis? Quan, Taihao Johnston, Andrew Gudjonsson, Johann Fisher, Gary J. J Invest Dermatol Article The complex pathogenesis of psoriasis is still not fully understood. The study by Sun et al. (Sun et al., 2015) in this issue of the journal suggests that CYR61(now named CCN1), a secreted matricellular protein, plays a role in the pathogenesis of psoriasis, and thus targeting CCN1 represents a potential therapeutic strategy in its treatment. 2015-11 /pmc/articles/PMC4641044/ /pubmed/26548486 http://dx.doi.org/10.1038/jid.2015.300 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Quan, Taihao
Johnston, Andrew
Gudjonsson, Johann
Fisher, Gary J.
CYR61/CCN1: A novel mediator of epidermal hyperplasia and inflammation in psoriasis?
title CYR61/CCN1: A novel mediator of epidermal hyperplasia and inflammation in psoriasis?
title_full CYR61/CCN1: A novel mediator of epidermal hyperplasia and inflammation in psoriasis?
title_fullStr CYR61/CCN1: A novel mediator of epidermal hyperplasia and inflammation in psoriasis?
title_full_unstemmed CYR61/CCN1: A novel mediator of epidermal hyperplasia and inflammation in psoriasis?
title_short CYR61/CCN1: A novel mediator of epidermal hyperplasia and inflammation in psoriasis?
title_sort cyr61/ccn1: a novel mediator of epidermal hyperplasia and inflammation in psoriasis?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641044/
https://www.ncbi.nlm.nih.gov/pubmed/26548486
http://dx.doi.org/10.1038/jid.2015.300
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AT gudjonssonjohann cyr61ccn1anovelmediatorofepidermalhyperplasiaandinflammationinpsoriasis
AT fishergaryj cyr61ccn1anovelmediatorofepidermalhyperplasiaandinflammationinpsoriasis

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