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Characterization of [(99m)Tc]Duramycin as a SPECT Imaging Agent for Early Assessment of Tumor Apoptosis

PURPOSE: We investigated the usefulness of [(99m)Tc]duramycin for monitoring early response to cancer therapy in mice, with an eye towards clinical translation. PROCEDURES: [(99m)Tc]Duramycin was injected in healthy CD1−/− mice to estimate human [(99m)Tc]duramycin radiation dose. [(99m)Tc]Duramycin...

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Detalles Bibliográficos
Autores principales: Elvas, Filipe, Vangestel, Christel, Rapic, Sara, Verhaeghe, Jeroen, Gray, Brian, Pak, Koon, Stroobants, Sigrid, Staelens, Steven, wyffels, Leonie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641155/
https://www.ncbi.nlm.nih.gov/pubmed/25896815
http://dx.doi.org/10.1007/s11307-015-0852-6