Evaluation of a Novel Tc-99m Labelled Vitamin B(12) Derivative for Targeting Escherichia coli and Staphylococcus aureus In Vitro and in an Experimental Foreign-Body Infection Model

PURPOSE: Vitamin B(12) (cyanocobalamin, Cbl) is accumulated by rapidly replicating prokaryotic and eukaryotic cells. We investigated the potential of a Tc-99m labelled Cbl derivative ([(99m)Tc]PAMA(4)-Cbl) for targeting infections caused by Escherichia coli and Staphylococcus aureus. In vitro bindin...

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Detalles Bibliográficos
Autores principales: Baldoni, Daniela, Waibel, Robert, Bläuenstein, Peter, Galli, Filippo, Iodice, Violetta, Signore, Alberto, Schibli, Roger, Trampuz, Andrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641156/
https://www.ncbi.nlm.nih.gov/pubmed/25860122
http://dx.doi.org/10.1007/s11307-015-0832-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641156/
https://www.ncbi.nlm.nih.gov/pubmed/25860122
http://dx.doi.org/10.1007/s11307-015-0832-x

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