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Nosocomial Methemoglobinemia Resulting from Self-Administration of Benzocaine Spray
Methemoglobinemia is life-threatening and bears pathognomonic signs difficult to diagnose in real time. Local anesthetics are widely used and are known for eliciting this condition. We report a case of methemoglobinemia secondary to self-administered use of benzocaine spray. A 27-year-old woman was...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641172/ https://www.ncbi.nlm.nih.gov/pubmed/26605091 http://dx.doi.org/10.1155/2015/685304 |
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author | Hoffman, Christopher Abubakar, Hawa Kalikiri, Pramood Green, Michael |
author_facet | Hoffman, Christopher Abubakar, Hawa Kalikiri, Pramood Green, Michael |
author_sort | Hoffman, Christopher |
collection | PubMed |
description | Methemoglobinemia is life-threatening and bears pathognomonic signs difficult to diagnose in real time. Local anesthetics are widely used and are known for eliciting this condition. We report a case of methemoglobinemia secondary to self-administered use of benzocaine spray. A 27-year-old woman was found to be in respiratory distress during postoperative recovery. After desaturation persisted, arterial blood gas yielded a methemoglobin level of 47%. The patient was successfully treated with intravenous methylene blue. Review of the events revealed self-administered doses of benzocaine spray to alleviate discomfort from a nasogastric tube. We review this case in detail in addition to discussing methemoglobinemia and its relevant biochemistry, pathophysiology, clinical presentation, and medical management. Given the recognized risk of methemoglobinemia associated with benzocaine use, we recommend its removal from the market in favor of safer alternatives. |
format | Online Article Text |
id | pubmed-4641172 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-46411722015-11-24 Nosocomial Methemoglobinemia Resulting from Self-Administration of Benzocaine Spray Hoffman, Christopher Abubakar, Hawa Kalikiri, Pramood Green, Michael Case Rep Anesthesiol Case Report Methemoglobinemia is life-threatening and bears pathognomonic signs difficult to diagnose in real time. Local anesthetics are widely used and are known for eliciting this condition. We report a case of methemoglobinemia secondary to self-administered use of benzocaine spray. A 27-year-old woman was found to be in respiratory distress during postoperative recovery. After desaturation persisted, arterial blood gas yielded a methemoglobin level of 47%. The patient was successfully treated with intravenous methylene blue. Review of the events revealed self-administered doses of benzocaine spray to alleviate discomfort from a nasogastric tube. We review this case in detail in addition to discussing methemoglobinemia and its relevant biochemistry, pathophysiology, clinical presentation, and medical management. Given the recognized risk of methemoglobinemia associated with benzocaine use, we recommend its removal from the market in favor of safer alternatives. Hindawi Publishing Corporation 2015 2015-10-28 /pmc/articles/PMC4641172/ /pubmed/26605091 http://dx.doi.org/10.1155/2015/685304 Text en Copyright © 2015 Christopher Hoffman et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Hoffman, Christopher Abubakar, Hawa Kalikiri, Pramood Green, Michael Nosocomial Methemoglobinemia Resulting from Self-Administration of Benzocaine Spray |
title | Nosocomial Methemoglobinemia Resulting from Self-Administration of Benzocaine Spray |
title_full | Nosocomial Methemoglobinemia Resulting from Self-Administration of Benzocaine Spray |
title_fullStr | Nosocomial Methemoglobinemia Resulting from Self-Administration of Benzocaine Spray |
title_full_unstemmed | Nosocomial Methemoglobinemia Resulting from Self-Administration of Benzocaine Spray |
title_short | Nosocomial Methemoglobinemia Resulting from Self-Administration of Benzocaine Spray |
title_sort | nosocomial methemoglobinemia resulting from self-administration of benzocaine spray |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641172/ https://www.ncbi.nlm.nih.gov/pubmed/26605091 http://dx.doi.org/10.1155/2015/685304 |
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