Cargando…

MPNs as Inflammatory Diseases: The Evidence, Consequences, and Perspectives

In recent years the evidence is increasing that chronic inflammation may be an important driving force for clonal evolution and disease progression in the Philadelphia-negative myeloproliferative neoplasms (MPNs), essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF). Abnorm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hasselbalch, Hans Carl, Bjørn, Mads Emil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641200/ https://www.ncbi.nlm.nih.gov/pubmed/26604428 http://dx.doi.org/10.1155/2015/102476

Ejemplares similares

Cytokine Profiling as a Novel Complementary Tool to Predict Prognosis in MPNs?
por: Hasselbalch, Hans C.
Publicado: (2020)

Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development
por: Andersen, Morten, et al.
Publicado: (2017)

The Role of Reactive Oxygen Species in Myelofibrosis and Related Neoplasms
por: Bjørn, Mads Emil, et al.
Publicado: (2015)

Patients with MPNs and retinal drusen show signs of complement system dysregulation and a high degree of chronic low-grade inflammation
por: Liisborg, Charlotte, et al.
Publicado: (2021)

The impact of ruxolitinib treatment on inflammation-mediated comorbidities in myelofibrosis and related neoplasms
por: Bjørn, Mads Emil, et al.
Publicado: (2015)

Biology and therapeutic targeting of molecular mechanisms in MPNs
por: How, Joan, et al.
Publicado: (2023)

A novel integrated biomarker index for the assessment of hematological responses in MPNs during treatment with hydroxyurea and interferon‐alpha2
por: Dam, Marc J. B., et al.
Publicado: (2022)

Recent Advances of Fe(III)/Fe(II)-MPNs in Biomedical Applications
por: Chen, Weipeng, et al.
Publicado: (2023)

A tale of two alleles: TP53 and transformation in MPNs
por: Brierley, Charlotte, et al.
Publicado: (2022)

Magnetic Peripheral Nerve Stimulation (mPNS) for Chronic Pain
por: Bedder, Marshall, et al.
Publicado: (2023)

Mathematical Modeling of MPNs Offers Understanding and Decision Support for Personalized Treatment
por: Ottesen, Johnny T., et al.
Publicado: (2020)

Perspectives on interferon-alpha in the treatment of polycythemia vera and related myeloproliferative neoplasms: minimal residual disease and cure?
por: Hasselbalch, Hans Carl, et al.
Publicado: (2018)

Next Generation Sequencing in MPNs. Lessons from the Past and Prospects for Use as Predictors of Prognosis and Treatment Responses
por: Skov, Vibe
Publicado: (2020)

Predictive Value of Kozak Gene Polymorphism for Thrombosis in Patients with Philadelphia-Negative MPNs
por: El-Ghonemy, Mohamed Sabry, et al.
Publicado: (2021)

A JAK of all trades: how global phosphoproteomics reveal the Achilles heel of MPNs
por: Schnoeder, Tina M., et al.
Publicado: (2021)

Correction Notice: Cytokine Profiling as a Novel Complementary Tool to Predict Prognosis in MPNs?
Publicado: (2020)

Cancer Immune Therapy for Philadelphia Chromosome-Negative Chronic Myeloproliferative Neoplasms
por: Holmström, Morten Orebo, et al.
Publicado: (2020)

Myeloproliferative blood cancers as a human neuroinflammation model for development of Alzheimer’s disease: evidences and perspectives
por: Hasselbalch, Hans C., et al.
Publicado: (2020)

Additional Genetic Alterations and Clonal Evolution of MPNs with Double Mutations on the MPL Gene: Two Case Reports
por: Pennisi, Maria Stella, et al.
Publicado: (2023)

Myeloproliferative neoplasms (MPNs) have a significant impact on patients’ overall health and productivity: the MPN Landmark survey
por: Mesa, Ruben, et al.
Publicado: (2016)

The impact of myeloproliferative neoplasms (MPNs) on patient quality of life and productivity: results from the international MPN Landmark survey
por: Harrison, Claire N., et al.
Publicado: (2017)

Measuring menstrual hygiene experience: development and validation of the Menstrual Practice Needs Scale (MPNS-36) in Soroti, Uganda
por: Hennegan, Julie, et al.
Publicado: (2020)

Whole-genome CRISPR screening identifies N-glycosylation as a genetic and therapeutic vulnerability in CALR-mutant MPNs
por: Jutzi, Jonas S., et al.
Publicado: (2022)

Impact of Myeloproliferative neoplasms on patients’ employment status and work productivity in the United States: results from the living with MPNs survey
por: Yu, Jingbo, et al.
Publicado: (2018)

Unlocking the Role of Endothelial MPL Receptor and JAK2V617F Mutation: Insights into Cardiovascular Dysfunction in MPNs and CHIP
por: Zhang, Haotian, et al.
Publicado: (2023)

Relationship between symptom burden and disability leave among patients with myeloproliferative neoplasms (MPNs): findings from the Living with MPN patient survey
por: Yu, Jingbo, et al.
Publicado: (2019)

Oxygen-18 Kinetic Isotope Effects of Nonheme Iron Enzymes HEPD and MPnS Support Iron(III) Superoxide as the Hydrogen Abstraction Species
por: Zhu, Hui, et al.
Publicado: (2015)

A comparison of qPCR and ddPCR used for quantification of the JAK2 V617F allele burden in Ph negative MPNs
por: Link-Lenczowska, Dorota, et al.
Publicado: (2018)

Whole Blood Transcriptional Profiling Reveals Deregulation of Oxidative and Antioxidative Defence Genes in Myelofibrosis and Related Neoplasms. Potential Implications of Downregulation of Nrf2 for Genomic Instability and Disease Progression
por: Hasselbalch, Hans Carl, et al.
Publicado: (2014)

Thiopurines and inflammatory bowel disease: Current evidence and a historical perspective
por: Axelrad, Jordan E, et al.
Publicado: (2016)

Anti-Integrins for the Treatment of Inflammatory Bowel Disease: Current Evidence and Perspectives
por: Gubatan, John, et al.
Publicado: (2021)

Ocular Manifestations in Patients with Philadelphia-Negative Myeloproliferative Neoplasms
por: Liisborg, Charlotte, et al.
Publicado: (2020)

Revisiting Circulating Extracellular Matrix Fragments as Disease Markers in Myelofibrosis and Related Neoplasms
por: Hasselbalch, Hans Carl, et al.
Publicado: (2023)

Differences in treatment goals and perception of symptom burden between patients with myeloproliferative neoplasms (MPNs) and hematologists/oncologists in the United States: Findings from the MPN Landmark survey
por: Mesa, Ruben A., et al.
Publicado: (2016)

Human malarial disease: a consequence of inflammatory cytokine release
por: Clark, Ian A, et al.
Publicado: (2006)

Transcriptional Profiling of Whole Blood Identifies a Unique 5-Gene Signature for Myelofibrosis and Imminent Myelofibrosis Transformation
por: Hasselbalch, Hans Carl, et al.
Publicado: (2014)

Elevated levels of oxidized nucleosides in individuals with the JAK2V617F mutation from a general population study
por: Sørensen, Anders L., et al.
Publicado: (2021)

Revalidation and adaptation of the Menstrual Practice Needs Scale (MPNS) in a cross-sectional survey to measure the menstrual experiences of adult women working in Mukono District, Uganda
por: Hennegan, Julie, et al.
Publicado: (2022)

New Perspectives of Interferon-alpha2 and Inflammation in Treating Philadelphia-negative Chronic Myeloproliferative Neoplasms
por: Hasselbalch, Hans C., et al.
Publicado: (2021)

Utilization of vinasses as soil amendment: consequences and perspectives
por: Moran-Salazar, R. G., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_fmc8juk6hbt0gsqqh3e3f8sr4p