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Current trends in treatment of hypertension in Karachi and cost minimization possibilities

OBJECTIVE: This study finds out drug usage trends in Stage I Hypertensive Patients without any compelling indications in Karachi, deviations of current practices from evidence based antihypertensive therapeutic guidelines and looks for cost minimization opportunities. METHODS: In the present study c...

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Autores principales: Hussain, Izhar M., Naqvi, Baqir S., Qasim, Rao M., Ali, Nasir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641248/
https://www.ncbi.nlm.nih.gov/pubmed/26648979
http://dx.doi.org/10.12669/pjms.315.7438
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author Hussain, Izhar M.
Naqvi, Baqir S.
Qasim, Rao M.
Ali, Nasir
author_facet Hussain, Izhar M.
Naqvi, Baqir S.
Qasim, Rao M.
Ali, Nasir
author_sort Hussain, Izhar M.
collection PubMed
description OBJECTIVE: This study finds out drug usage trends in Stage I Hypertensive Patients without any compelling indications in Karachi, deviations of current practices from evidence based antihypertensive therapeutic guidelines and looks for cost minimization opportunities. METHODS: In the present study conducted during June 2012 to August 2012, two sets were used. Randomized stratified independent surveys were conducted in doctors and general population - including patients, using pretested questionnaires. Sample sizes for doctors and general population were 100 and 400 respectively. Statistical analysis was conducted on Statistical Package for Social Science (SPSS). Financial impact was also analyzed. RESULTS: On the basis of patients’ doctors’ feedback, Beta Blockers, and Angiotensin Converting Enzyme Inhibitors were used more frequently than other drugs. Thiazides and low-priced generics were hardly prescribed. Beta blockers were prescribed widely and considered cost effective. This trend increases cost by two to ten times. CONCLUSION: Feedbacks showed that therapeutic guidelines were not followed by the doctors practicing in the community and hospitals in Karachi. Thiazide diuretics were hardly used. Beta blockers were widely prescribed. High priced market leaders or expensive branded generics were commonly prescribed. Therefore, there are great opportunities for cost minimization by using evidence-based clinically effective and safe medicines.
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spelling pubmed-46412482015-12-08 Current trends in treatment of hypertension in Karachi and cost minimization possibilities Hussain, Izhar M. Naqvi, Baqir S. Qasim, Rao M. Ali, Nasir Pak J Med Sci Original Article OBJECTIVE: This study finds out drug usage trends in Stage I Hypertensive Patients without any compelling indications in Karachi, deviations of current practices from evidence based antihypertensive therapeutic guidelines and looks for cost minimization opportunities. METHODS: In the present study conducted during June 2012 to August 2012, two sets were used. Randomized stratified independent surveys were conducted in doctors and general population - including patients, using pretested questionnaires. Sample sizes for doctors and general population were 100 and 400 respectively. Statistical analysis was conducted on Statistical Package for Social Science (SPSS). Financial impact was also analyzed. RESULTS: On the basis of patients’ doctors’ feedback, Beta Blockers, and Angiotensin Converting Enzyme Inhibitors were used more frequently than other drugs. Thiazides and low-priced generics were hardly prescribed. Beta blockers were prescribed widely and considered cost effective. This trend increases cost by two to ten times. CONCLUSION: Feedbacks showed that therapeutic guidelines were not followed by the doctors practicing in the community and hospitals in Karachi. Thiazide diuretics were hardly used. Beta blockers were widely prescribed. High priced market leaders or expensive branded generics were commonly prescribed. Therefore, there are great opportunities for cost minimization by using evidence-based clinically effective and safe medicines. Professional Medical Publications 2015 /pmc/articles/PMC4641248/ /pubmed/26648979 http://dx.doi.org/10.12669/pjms.315.7438 Text en Copyright: © Pakistan Journal of Medical Sciences http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Hussain, Izhar M.
Naqvi, Baqir S.
Qasim, Rao M.
Ali, Nasir
Current trends in treatment of hypertension in Karachi and cost minimization possibilities
title Current trends in treatment of hypertension in Karachi and cost minimization possibilities
title_full Current trends in treatment of hypertension in Karachi and cost minimization possibilities
title_fullStr Current trends in treatment of hypertension in Karachi and cost minimization possibilities
title_full_unstemmed Current trends in treatment of hypertension in Karachi and cost minimization possibilities
title_short Current trends in treatment of hypertension in Karachi and cost minimization possibilities
title_sort current trends in treatment of hypertension in karachi and cost minimization possibilities
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641248/
https://www.ncbi.nlm.nih.gov/pubmed/26648979
http://dx.doi.org/10.12669/pjms.315.7438
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