Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child Case report and review of the literature

BACKGROUND: Liver disease is rare in the course of mixed connective tissue disease. Most commonly liver steatosis or elevated liver function tests are reported and only a few cases of mixed connective tissue disease associated with autoimmune hepatitis were described. CASE PRESENTATION: We report a...

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Detalles Bibliográficos
Autores principales: Sedej, Katarina, Toplak, Nataša, Praprotnik, Marina, Luzar, Boštjan, Brecelj, Jernej, Avčin, Tadej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641331/
https://www.ncbi.nlm.nih.gov/pubmed/26554821
http://dx.doi.org/10.1186/s12969-015-0046-4
Descripción
Sumario:BACKGROUND: Liver disease is rare in the course of mixed connective tissue disease. Most commonly liver steatosis or elevated liver function tests are reported and only a few cases of mixed connective tissue disease associated with autoimmune hepatitis were described. CASE PRESENTATION: We report a case of an 11-year old boy with hepatitis on admission to the hospital and symptoms and signs of mixed connective tissue disease. Autoimmune hepatitis has been confirmed by liver biopsy. CONCLUSION: To the best of our knowledge this is the youngest patient with autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease.

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