Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child Case report and review of the literature

BACKGROUND: Liver disease is rare in the course of mixed connective tissue disease. Most commonly liver steatosis or elevated liver function tests are reported and only a few cases of mixed connective tissue disease associated with autoimmune hepatitis were described. CASE PRESENTATION: We report a...

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Autores principales: Sedej, Katarina, Toplak, Nataša, Praprotnik, Marina, Luzar, Boštjan, Brecelj, Jernej, Avčin, Tadej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641331/
https://www.ncbi.nlm.nih.gov/pubmed/26554821
http://dx.doi.org/10.1186/s12969-015-0046-4
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author Sedej, Katarina
Toplak, Nataša
Praprotnik, Marina
Luzar, Boštjan
Brecelj, Jernej
Avčin, Tadej
author_facet Sedej, Katarina
Toplak, Nataša
Praprotnik, Marina
Luzar, Boštjan
Brecelj, Jernej
Avčin, Tadej
author_sort Sedej, Katarina
collection PubMed
description BACKGROUND: Liver disease is rare in the course of mixed connective tissue disease. Most commonly liver steatosis or elevated liver function tests are reported and only a few cases of mixed connective tissue disease associated with autoimmune hepatitis were described. CASE PRESENTATION: We report a case of an 11-year old boy with hepatitis on admission to the hospital and symptoms and signs of mixed connective tissue disease. Autoimmune hepatitis has been confirmed by liver biopsy. CONCLUSION: To the best of our knowledge this is the youngest patient with autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease.
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spelling pubmed-46413312015-11-12 Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child Case report and review of the literature Sedej, Katarina Toplak, Nataša Praprotnik, Marina Luzar, Boštjan Brecelj, Jernej Avčin, Tadej Pediatr Rheumatol Online J Case Report BACKGROUND: Liver disease is rare in the course of mixed connective tissue disease. Most commonly liver steatosis or elevated liver function tests are reported and only a few cases of mixed connective tissue disease associated with autoimmune hepatitis were described. CASE PRESENTATION: We report a case of an 11-year old boy with hepatitis on admission to the hospital and symptoms and signs of mixed connective tissue disease. Autoimmune hepatitis has been confirmed by liver biopsy. CONCLUSION: To the best of our knowledge this is the youngest patient with autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease. BioMed Central 2015-11-10 /pmc/articles/PMC4641331/ /pubmed/26554821 http://dx.doi.org/10.1186/s12969-015-0046-4 Text en © Sedej et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Sedej, Katarina
Toplak, Nataša
Praprotnik, Marina
Luzar, Boštjan
Brecelj, Jernej
Avčin, Tadej
Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child Case report and review of the literature
title Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child Case report and review of the literature
title_full Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child Case report and review of the literature
title_fullStr Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child Case report and review of the literature
title_full_unstemmed Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child Case report and review of the literature
title_short Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child Case report and review of the literature
title_sort autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641331/
https://www.ncbi.nlm.nih.gov/pubmed/26554821
http://dx.doi.org/10.1186/s12969-015-0046-4
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