QQ-SNV: single nucleotide variant detection at low frequency by comparing the quality quantiles

BACKGROUND: Next generation sequencing enables studying heterogeneous populations of viral infections. When the sequencing is done at high coverage depth (“deep sequencing”), low frequency variants can be detected. Here we present QQ-SNV (http://sourceforge.net/projects/qqsnv), a logistic regression...

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Detalles Bibliográficos
Autores principales: Van der Borght, Koen, Thys, Kim, Wetzels, Yves, Clement, Lieven, Verbist, Bie, Reumers, Joke, van Vlijmen, Herman, Aerssens, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641353/
https://www.ncbi.nlm.nih.gov/pubmed/26554718
http://dx.doi.org/10.1186/s12859-015-0812-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641353/
https://www.ncbi.nlm.nih.gov/pubmed/26554718
http://dx.doi.org/10.1186/s12859-015-0812-9

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