Incorporating Virtual Reactions into a Logic-based Ligand-based Virtual Screening Method to Discover New Leads

The use of virtual screening has become increasingly central to the drug development pipeline, with ligand-based virtual screening used to screen databases of compounds to predict their bioactivity against a target. These databases can only represent a small fraction of chemical space, and this pape...

Descripción completa

Detalles Bibliográficos
Autores principales: Reynolds, Christopher R, Muggleton, Stephen H, Sternberg, Michael J E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641463/
https://www.ncbi.nlm.nih.gov/pubmed/26583052
http://dx.doi.org/10.1002/minf.201400162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641463/
https://www.ncbi.nlm.nih.gov/pubmed/26583052
http://dx.doi.org/10.1002/minf.201400162

Ejemplares similares