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Incorporating Virtual Reactions into a Logic-based Ligand-based Virtual Screening Method to Discover New Leads

The use of virtual screening has become increasingly central to the drug development pipeline, with ligand-based virtual screening used to screen databases of compounds to predict their bioactivity against a target. These databases can only represent a small fraction of chemical space, and this pape...

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Detalles Bibliográficos
Autores principales:	Reynolds, Christopher R, Muggleton, Stephen H, Sternberg, Michael J E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2015
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641463/ https://www.ncbi.nlm.nih.gov/pubmed/26583052 http://dx.doi.org/10.1002/minf.201400162

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